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h , Volcano plots of the fold change in mitochondrial metabolite abundance (log 2 ) versus P values (-log) from HEK-293T SLC25A39 knockout cell line expressing a vector control or SLC25A40 cDNA

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In the clinic, rectum spacer hydrogel implantation prevents rectal injury in prostate cancer radiotherapy (93)

These interactions result in the accumulation of lipoacylated proteins and a concomitant reduction in iron-sulfur (Fe-S) cluster proteins, thereby activating a protein-toxicity stress response that culminates in cell death (5)